Congenital Cytomegalovirus Infection in Japan

To the Editor: Cytomegalovirus is known to be the leading cause of congenital infection, with reported incidences ranging from 0.2 to 2.2 per cent of all live births. 1 The infection is mostly subclinical in the neonatal period, and less than 10 per cent of those infected have disease compatible with cytomegalic inclusion disease. We have studied the incidence of congenital cytomegalovirus infection in Japan, where 94 per cent of women become immune by the childbearing age. 2 Of 3627 neonates born at two hospitals in Sapporo, 19 (0.5 per cent) were identified as having intrauterine cytomegalovirus infection on the basis of . . . No extract is available for articles shorter than 400 words.