Immunoglobulins Associated With Human Platelets

Immunoglobulins Associated With Human Platelets

A technique for the accurate and reproducible quantitation of platelet associated immunoglobulins is described. The intact platelets of normal subjects were found to be associated with small quantities of Ig probably located at or near the platelet surface. Incubation of normal platelets in sera fro...

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Veröffentlicht in:Blood 1971-03, Vol.37 (3), p.316-322
Hauptverfasser: Mcmillan, Robert, Smith, Richard S., Longmire, Robert L., Yelenosky, Robert, Reid, Robert T., Craddock, Charles G.
Format: Artikel
Sprache:eng
Schlagworte:
Agammaglobulinemia - blood
Antigen-Antibody Complex
Blood Platelets - immunology
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Zusammenfassung:A technique for the accurate and reproducible quantitation of platelet associated immunoglobulins is described. The intact platelets of normal subjects were found to be associated with small quantities of Ig probably located at or near the platelet surface. Incubation of normal platelets in sera from some patients with immunologic purpura caused an increase in platelet immunoglobulin levels.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V37.3.316.316