Low tryptophan diets delay reproductive aging

Newly weaned female rats fed diets severely deficient in the essential amino acid tryptophan show marked delays in reproductive aging, with conception and delivery occurring as late as 36 months. The rate of aging in these rats seems inversely related to both their early growth rates and the accessi...

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Veröffentlicht in:Mechanisms of ageing and development 1983-11, Vol.23 (3), p.245-252
Hauptverfasser: Segall, Paul E., Timiras, Paola S., Walton, Judie R.
Format: Artikel
Sprache:eng
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Zusammenfassung:Newly weaned female rats fed diets severely deficient in the essential amino acid tryptophan show marked delays in reproductive aging, with conception and delivery occurring as late as 36 months. The rate of aging in these rats seems inversely related to both their early growth rates and the accessibility of brain tryptophan. The subsequent age retardation may depend on a reduction in both early cell loss and rate of brain maturation.
ISSN:0047-6374
1872-6216
DOI:10.1016/0047-6374(83)90024-6