The Complementary Roles of Brain Scintigraphy and Computed Tomography in Multiple Sclerosis

Cerebral computed tomography, with and without iodinated contrast, revealed the appearance and evolution of lesions in a 32–year–old man with multiple sclerosis. Two areas were enhanced with contrast, with one showing a mild mass effect and rim of enhancement. Serial brain scintigraphy using technetium–99m glucoheptonate, following the computed tomography, showed the appearance and regression of corresponding regions of increased uptake. Computed tomography one day prior to brain scintigraphy failed to demonstrate a region of increased accumulation of radiotracer. One week later, however, evidence of a corresponding unenhanced defect was noted on computed tomography. Clinical correlation is given additionally.