Vitamin C supplementation of total parenteral nutrition formulas

Vitamin C supplementation of total parenteral nutrition formulas

Twenty hospitalized adults on total parenteral nutrition (TPN) were studied for 15 days to assess the effects of daily vitamin C intake (350-2250 milligrams) on serum and urine vitamin C levels. Increases in serum vitamin C levels were observed but remained in the normal range; urine vitamin C level...

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Veröffentlicht in:JPEN. Journal of parenteral and enteral nutrition 1983-09, Vol.7 (5), p.465-469
Hauptverfasser: Abrahamian, Vasken, Kaminski, Mitchell V. Jr, Santiago, Gustavo Cruz
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
ascorbic acid
Ascorbic Acid - administration & dosage
Ascorbic Acid - metabolism
Biological and medical sciences
Drug Stability
Emergency and intensive care: injuries, diseases due to physical agents. Diving. Drowning. Disaster medicine
Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition
Female
Humans
Intensive care medicine
Light
Male
Medical sciences
Middle Aged
nutritional status
Parenteral Nutrition
Parenteral Nutrition, Total
Supplements (Nutrient)
total parenteral nutrition
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Beschreibung
Zusammenfassung:Twenty hospitalized adults on total parenteral nutrition (TPN) were studied for 15 days to assess the effects of daily vitamin C intake (350-2250 milligrams) on serum and urine vitamin C levels. Increases in serum vitamin C levels were observed but remained in the normal range; urine vitamin C levels were above normal in all but one of the patients. Intake of vitamin C resulted in a positive C balance which correlated with urine concentration. Eight hundred milligrams/day was the maximum vitamin C retained. Therefore, doses in excess of 1000 milligrams/day are not recommended. (kbc)
ISSN:0148-6071
1941-2444
DOI:10.1177/0148607183007005465