Healing of Tooth Extraction Wounds in Rats with Renal Hypertension. A Histological Study

The aim was to study bone formation in tooth extraction sockets of rats with experimentally induced renal hypertension. As soon as hypertension was detected the upper right incisor was extracted. The animals were killed at 3, 6, 9, 12, 18 and 21 days post-extraction. At day 9 the hypertensive animals showed bone formation with little osteoblastic activity, the bone was more cellular and had immature osteoblasts and endosteal cells without trabeculae formation. In the medullary spaces oedematous connective tissue, dilated vessels and undifferentiated cells were seen. We concluded that these animals presented a different pattern of bone formation when compared to the control animals.