SAFRACINS, NEW ANTITUMOR ANTIBIOTICS: I. PRODUCING ORGANISM, FERMENTATION AND ISOLATION

SAFRACINS, NEW ANTITUMOR ANTIBIOTICS: I. PRODUCING ORGANISM, FERMENTATION AND ISOLATION

Safracins, new antibiotics with a novel skeleton, were discovered in a culture broth of Pseudomonas sp. The producing organism has been identified as Pseudomonas fluorescens. Safracins A and B were isolated by ethyl acetate extraction and chromatography on silica gel.

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Veröffentlicht in:Journal of antibiotics 1983, Vol.36(10), pp.1279-1283
Hauptverfasser: IKEDA, YOSHIFUMI, IDEMOTO, HARUMI, HIRAYAMA, FUMIHIRO, YAMAMOTO, KATSUHIRO, IWAO, KAZUHIRO, ASAO, TOSHIMI, MUNAKATA, TOMOHIKO
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Antibiotics (antibacterial agents, antifungal agents)
Antibiotics, Antineoplastic - isolation & purification
Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents
Applied microbiology
Biological and medical sciences
Biotechnology
Carbohydrate Metabolism
Culture Media
Fermentation
Fundamental and applied biological sciences. Psychology
Health. Pharmaceutical industry
Industrial applications and implications. Economical aspects
Isoquinolines - biosynthesis
Isoquinolines - isolation & purification
Kinetics
Microbiology
Nitrogen - metabolism
Production of active biomolecules
Pseudomonas fluorescens
Pseudomonas fluorescens - classification
Pseudomonas fluorescens - growth & development
safracin
Structure-Activity Relationship
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Beschreibung
Zusammenfassung:Safracins, new antibiotics with a novel skeleton, were discovered in a culture broth of Pseudomonas sp. The producing organism has been identified as Pseudomonas fluorescens. Safracins A and B were isolated by ethyl acetate extraction and chromatography on silica gel.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.36.1279