Topical benzoyl peroxide increases the sebum excretion rate in patients with acne

Topical benzoyl peroxide increases the sebum excretion rate in patients with acne

SUMMARY Investigations on fifteen patients with acne showed that at the end of 1 and 2 months of treatment 5% benzoyl peroxide increased the sebum excretion rate by 22.5%. This rise in sebum excretion is probably due to the comedolytic activity of benzoyl peroxide which will influence the pooling of...

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Veröffentlicht in:British journal of dermatology (1951) 1983-11, Vol.109 (5), p.577-579
Hauptverfasser: CUNLIFFE, W. J., STAINTON, C., FORSTER, R. A.
Format: Artikel
Sprache:eng
Schlagworte:
Acne Vulgaris - drug therapy
Acne Vulgaris - metabolism
Administration, Topical
Adolescent
Adult
Benzoyl Peroxide - administration & dosage
Benzoyl Peroxide - therapeutic use
Female
Humans
Male
Peroxides - administration & dosage
Sebum - drug effects
Sebum - metabolism
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Zusammenfassung:SUMMARY Investigations on fifteen patients with acne showed that at the end of 1 and 2 months of treatment 5% benzoyl peroxide increased the sebum excretion rate by 22.5%. This rise in sebum excretion is probably due to the comedolytic activity of benzoyl peroxide which will influence the pooling of sebum in the upper reaches of the pilosebaceous duct.
ISSN:0007-0963
1365-2133
DOI:10.1111/j.1365-2133.1983.tb07682.x