Retinoic acid binding protein in human and experimental pancreatic carcinomas in hamsters

Cytoplasmic retinoic acid binding protein (cRABP) is present in human fetal pancreas and becomes nondetectable in the normal adult pancreas. The binding protein for retinoic acid becomes apparent again in pancreatic cancer. Similar fluctuations in the content of cRABP occur in the hamster. The bindi...

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Veröffentlicht in:	Annals of clinical and laboratory science 1983-09, Vol.13 (5), p.400-406
Hauptverfasser:	Brandes, M, Gesell, M S, Ueda, H, Millan, J C, Quinlan, R M, Ernst, C, Sindelar, W F, Kurman, C C, Harris, S, Brandes, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - analysis Adenocarcinoma - pathology Aging Animals Carrier Proteins - analysis Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology Cricetinae Female Fetus Humans Mesocricetus Pancreas - analysis Pancreatic Neoplasms - analysis Pancreatic Neoplasms - pathology Pregnancy Receptors, Retinoic Acid
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Zusammenfassung:	Cytoplasmic retinoic acid binding protein (cRABP) is present in human fetal pancreas and becomes nondetectable in the normal adult pancreas. The binding protein for retinoic acid becomes apparent again in pancreatic cancer. Similar fluctuations in the content of cRABP occur in the hamster. The binding protein is undetectable in the normal adult hamster pancreas, while it was detected in several transplantable adenocarcinomas in the Syrian golden hamster.
ISSN:	0091-7370