Serum erythropoietin changes in cats with feline leukemia virus-induced erythroid aplasia

Erythropoietin concentrations were increased significantly (p < 0.025) in nine cats with natural feline leukemia virus infection and associated erythroid aplasia compared to six clinically normal cats. Adult cats experimentally inoculated with the Kawakami-Theilen isolate of feline leukemia virus...

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Veröffentlicht in:	Veterinary pathology 1983-09, Vol.20 (5), p.548-552
Hauptverfasser:	Kociba, G. J., Lange, R. D., Dunn, C. D. R., Hoover, E. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Aplastic - blood Anemia, Aplastic - veterinary Animals Cat Diseases - blood Cats Erythropoietin - blood feline leukemia virus Female Hematocrit - veterinary Leukemia - blood Leukemia - veterinary Leukemia Virus, Feline Male Methylprednisolone - administration & dosage Methylprednisolone - analogs & derivatives Space life sciences Specific Pathogen-Free Organisms
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Beschreibung
Zusammenfassung:	Erythropoietin concentrations were increased significantly (p < 0.025) in nine cats with natural feline leukemia virus infection and associated erythroid aplasia compared to six clinically normal cats. Adult cats experimentally inoculated with the Kawakami-Theilen isolate of feline leukemia virus developed a progressive simultaneous increase in erythropoietin activity and decrease in packed cell volume. These findings indicate that erythroid aplasia associated with feline leukemia virus infection is not caused by a failure in erythropoietin production.
ISSN:	0300-9858 1544-2217
DOI:	10.1177/030098588302000506