Treatment of Constitutional Delay of Growth and Adolescence with Human Growth Hormone

Treatment of Constitutional Delay of Growth and Adolescence with Human Growth Hormone

Abstract Constitutional delay of growth and adolescence is caused by continuous diminution of spontaneous hGH-secretion as was proved by measuring hGH-levels in deep sleep by night. Therefore, treatment by hGH is a replacement therapy. Thirteen patients underwent hGH long-term therapy, 12 with good...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Klinische Pädiatrie 1983-09, Vol.195 (5), p.309-316
1. Verfasser: Bierich, J. R.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Child
Child, Preschool
Female
Growth Disorders - drug therapy
Growth Hormone - blood
Growth Hormone - therapeutic use
Humans
Male
ORIGINALIEN
Time Factors
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract Constitutional delay of growth and adolescence is caused by continuous diminution of spontaneous hGH-secretion as was proved by measuring hGH-levels in deep sleep by night. Therefore, treatment by hGH is a replacement therapy. Thirteen patients underwent hGH long-term therapy, 12 with good success. On average we observed doubling of the previous growth velocity, in the most favourable case an increase from 3.5 cm to 14.7 cm per year. Predicted adult height rose in 5 cases.
ISSN:0300-8630
1439-3824
DOI:10.1055/s-2008-1034388