Malignant histiocytosis

The clinical features, therapy, and hospital course of ten consecutive patients with malignant histiocytosis (MH) are presented. The value of bone marrow aspiration for the diagnosis is discussed. The patient's performance status as described in this report by the organ dysfunction score may pr...

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Veröffentlicht in:Cancer 1983-11, Vol.52 (10), p.1904-1910
Hauptverfasser: Esseltine, Dixie W., De Leeuw, NANNIE K. M., Berry, Gerry R.
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container_end_page 1910
container_issue 10
container_start_page 1904
container_title Cancer
container_volume 52
creator Esseltine, Dixie W.
De Leeuw, NANNIE K. M.
Berry, Gerry R.
description The clinical features, therapy, and hospital course of ten consecutive patients with malignant histiocytosis (MH) are presented. The value of bone marrow aspiration for the diagnosis is discussed. The patient's performance status as described in this report by the organ dysfunction score may predict survival and response to chemotherapy. The literature on chemotherapy in this disease is reviewed. Combination chemotherapy may be the best approach to treatment, but there is little experience with single agents. There is a great need for better characterization of the malignant cell in this disorder.
doi_str_mv 10.1002/1097-0142(19831115)52:10<1904::AID-CNCR2820521022>3.0.CO;2-K
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Myelofibrosis</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Diseases - drug therapy</subject><subject>Lymphatic Diseases - pathology</subject><subject>Macrophages - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Radiography</subject><subject>Respiratory Tract Diseases - diagnostic imaging</subject><subject>Respiratory Tract Diseases - pathology</subject><subject>Splenomegaly</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkM1rGzEUxEVISJ2Pc0-BHkJID-u897TaldxQCOt84bSGkEIOgYdW1qZb1l53ZVP832ddO4b0EOhJSPPTMDNC9BG6CEBnCCaNAGM6RaMlIqrPinoI52gg7vUubvtR9j27J02gCIHoq-xCNxt-oWiwJTqb79uiAwA6UrF8_CD2QvjVXlNSclfsJlLFMaYd8fGbrcrniZ3MPv0sw6ys3WJWhzIciJ3CVsEfrs998ePq8iG7ie6G17fZxV3kYkwoQmuMHFlvJY2UJpdTrr0ZWczbhyS1OsmVNh48QuJ0XkCBTjktPSRFqopY7ouTle-0qX_PfZjxuAzOV5Wd-HoeWENi2tqmBZ9WoGvqEBpf8LQpx7ZZMAIvd-NlcV4W59fdWNFftTVgbnfjt7uxZOBsyMSD1v5onWOej_1oY74eqtWP17oNzlZFYyeuDBvMxAlJWmLPK-xPWfnFf0Z8N-E_inwB9hiV4A</recordid><startdate>19831115</startdate><enddate>19831115</enddate><creator>Esseltine, Dixie W.</creator><creator>De Leeuw, NANNIE K. 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subjects Adult
Aged
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Autopsy
Biological and medical sciences
Blood Cell Count
Bone Marrow - pathology
Fever - pathology
Hematologic and hematopoietic diseases
Hepatomegaly
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Lymph Nodes - pathology
Lymphatic Diseases - drug therapy
Lymphatic Diseases - pathology
Macrophages - pathology
Male
Medical sciences
Middle Aged
Radiography
Respiratory Tract Diseases - diagnostic imaging
Respiratory Tract Diseases - pathology
Splenomegaly
title Malignant histiocytosis
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