New embolization method using estrogen: Effect of estrogen on microcirculation

To ascertain the mechanism of action of estrogen administered by a new embolization method, developed by the authors as a treatment method for dural arteriovenous malformations, conjugated estrogens were injected into the mesenteric artery of rabbits, and microcirculatory changes in the dominant are...

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Veröffentlicht in:	Surgical neurology 1983-10, Vol.20 (4), p.269-275
Hauptverfasser:	Nagamine, Yoshihide, Komatsu, Shinro, Suzuki, Jiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain - blood supply Conjugated estrogen Diseases of the nervous system Dura Mater Embolization Embolization, Therapeutic Estrogens - administration & dosage Intracranial Arteriovenous Malformations - therapy Medical sciences Microcirculation Microcirculation - drug effects Rabbits Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Sludging Stasis
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Beschreibung
Zusammenfassung:	To ascertain the mechanism of action of estrogen administered by a new embolization method, developed by the authors as a treatment method for dural arteriovenous malformations, conjugated estrogens were injected into the mesenteric artery of rabbits, and microcirculatory changes in the dominant areas were studied biomicroscopically. Conjugated estrogen induced sludging and stasis in the microcirculation, approximately in proportion to the concentration and dose.
ISSN:	0090-3019 1879-3339
DOI:	10.1016/0090-3019(83)90077-0