Eukaryotic genome: Model considerations

The paper presents a new model of chromosome structure based on the assumption that multiple circular subunits of DNA exist. The essential difference with previously described models is that circular DNA unit forms a central chromosome axis. Chromosome configurations during various phases of the cel...

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Veröffentlicht in:Journal of theoretical biology 1983-08, Vol.103 (3), p.379-403
1. Verfasser: Wojcierowski, Jacek K.
Format: Artikel
Sprache:eng
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Zusammenfassung:The paper presents a new model of chromosome structure based on the assumption that multiple circular subunits of DNA exist. The essential difference with previously described models is that circular DNA unit forms a central chromosome axis. Chromosome configurations during various phases of the cell cycle depend on the various conformations of this central integrating unit. The described model can be generalized for all haploid set of eukaryotic nucleus. Some aspects of the chromosome structure and their functions have been discussed.
ISSN:0022-5193
1095-8541
DOI:10.1016/0022-5193(83)90293-X