Five new TaqI DRB1 polymorphisms

Five new TaqI DRB1 polymorphisms

Five new restriction fragment length polymorphisms (RFLPs) using TaqI and a DRβ probe have been found in Caucasian individuals. The families of these individuals have been tissue typed by serological and RFLP methods. The new RFLPs are similar to previously established RFLPs except for the size of o...

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Veröffentlicht in:Human immunology 1991-06, Vol.31 (2), p.145-147
Hauptverfasser: Middleton, D., Savage, D.A., Cullen, C., Martin, J.
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Blood Donors
DNA - analysis
DNA-Directed DNA Polymerase - genetics
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Histocompatibility Antigens Class II - genetics
HLA-DR Antigens - genetics
HLA-DRB1 Chains
Humans
Molecular immunology
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Taq Polymerase
Techniques
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Zusammenfassung:Five new restriction fragment length polymorphisms (RFLPs) using TaqI and a DRβ probe have been found in Caucasian individuals. The families of these individuals have been tissue typed by serological and RFLP methods. The new RFLPs are similar to previously established RFLPs except for the size of one fragment in each instance.
ISSN:0198-8859
1879-1166
DOI:10.1016/0198-8859(91)90018-5