Contamination of Donor Cornea: Postpenetrating Keratoplasty Endophthalmitis

Nine cases (0.41%) of bacterial and fungal endophthalmitis developed out of a total of 2,210 consecutive penetrating keratoplasties performed between November 1983 and April 1989. Five of the nine cases (0.23%) had endophthalmitis related to donor tissue contamination. The donor tissue of these case...

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Veröffentlicht in:Cornea 1991-05, Vol.10 (3), p.217-220
Hauptverfasser: Antonios, Sobhi R, Cameron, James A, Badr, Ihsan A, Habash, Nadim R, Cotter, John B
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Sprache:eng
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Zusammenfassung:Nine cases (0.41%) of bacterial and fungal endophthalmitis developed out of a total of 2,210 consecutive penetrating keratoplasties performed between November 1983 and April 1989. Five of the nine cases (0.23%) had endophthalmitis related to donor tissue contamination. The donor tissue of these cases had a storage time of>5 days. A retrospective analysis of 1,399 consecutive corneoscleral rim cultures showed a contamination rate of 29%. The most common organisms isolated were Propionibacterium 26%, diphtheroids 24%, Staphylococcus epidermidis 22%, and fungi 9%. There is a statistically significant increase (p < 0.005) in the percentage of contaminated donor rims with a preservation time of more than five days. The risk of developing endophthalmitis is 12 times greater with a positive donor rim culture. Prolonged preservation of donor tissue can be a risk factor in developing endophthalmitis.
ISSN:0277-3740
1536-4798
DOI:10.1097/00003226-199105000-00006