Congenital neuroblastoma and placental metastases

Thus far ten patients with connatal neuroblastoma and metastases in the placenta have been reported. Our patient suffered from neuroblastoma stage IV-S and expired on the first day of life due to hepatic failure from massive metastatic involvement of this organ. Metastases from the placenta into the mother have thus far never occurred, neither in our case nor in any patient reported in the literature.