Vasopressin and memory

Both vasopressin and oxytocin have been shown to exert behavioral effects by a direct action on the central nervous system. Oxytocin appears to have amnestic properties as concluded among others from the attenuation of passive avoidance behavior and the facilitation of extinction of active avoidance...

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Veröffentlicht in:	Pharmacology & therapeutics (Oxford) 1983, Vol.20 (3), p.437-458
Hauptverfasser:	van Wimersma Greidanus, Tjeerd B., van Ree, Jan M., de Wied, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - pharmacology Avoidance Learning - physiology Behavior, Animal - physiology Brain - physiology Diabetes Insipidus - physiopathology Humans Injections, Intraventricular Memory - physiology Structure-Activity Relationship Vasopressins - administration & dosage Vasopressins - immunology Vasopressins - pharmacology Vasopressins - physiology
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Beschreibung
Zusammenfassung:	Both vasopressin and oxytocin have been shown to exert behavioral effects by a direct action on the central nervous system. Oxytocin appears to have amnestic properties as concluded among others from the attenuation of passive avoidance behavior and the facilitation of extinction of active avoidance behavior following intracerebroventricular administration of this neuropeptide. In contrast a variety of behavioral effects have been described indicating that vasopressin stimulates memory function. In this review these effects of vasopressin will be described in detail.
ISSN:	0163-7258 1879-016X
DOI:	10.1016/0163-7258(83)90036-0