Nicotine exerts differential effects on different CA1 hippocampal cell types
The effects of (−) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects...
Gespeichert in:
| Veröffentlicht in: | Brain research 1991-02, Vol.540 (1), p.287-290 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 290 |
|---|---|
| container_issue | 1 |
| container_start_page | 287 |
| container_title | Brain research |
| container_volume | 540 |
| creator | Reece, Laura J. Schwartzkroin, Philip A. |
| description | The effects of (−) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects of nicotine on pyramidal cells may thus be a product of complex local circuit interactions. |
| doi_str_mv | 10.1016/0006-8993(91)90520-6 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_80628284</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0006899391905206</els_id><sourcerecordid>80628284</sourcerecordid><originalsourceid>FETCH-LOGICAL-c418t-7be4cf5ed2e0a1f91dcf0dc7c3ad97caf1dc3e1cb9ad3cf43bb9ca01b676a9513</originalsourceid><addsrcrecordid>eNqFkUFv1DAQhS1E1W5b_gGVcqGCQ1pPnDj2BalaUUBatZdytpzxWBhlk2BnEf33dbqr9gYn22_ePD19Zuw98CvgIK8557JUWouPGj5p3lS8lG_YClRblbKq-Vu2erGcsNOUfuWnEJofs-OKN7WsYMU2dwHHOQxU0F-Kcypc8J4iDXOwfUH5jlkch1e9WN9A8TNM04h2O2UTUt8X8-NE6Zwdedsnenc4z9iP2y8P62_l5v7r9_XNpsQa1Fy2HdXoG3IVcQteg0PPHbYorNMtWp8FQYCdtk6gr0XXabQcOtlKqxsQZ-xynzvF8feO0my2IS017EDjLhnFZaUqVf_XCI3SoJTIxnpvxDimFMmbKYatjY8GuFlomwWlWVAaDeaZtpF57eKQv-u25F6WDnjz_MNhbhPa3kc7YEiv2VoKaJul5-e9jzK1P4GiSRhoQHIh5g8wbgz_LvIEvumcgw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>15891883</pqid></control><display><type>article</type><title>Nicotine exerts differential effects on different CA1 hippocampal cell types</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Reece, Laura J. ; Schwartzkroin, Philip A.</creator><creatorcontrib>Reece, Laura J. ; Schwartzkroin, Philip A.</creatorcontrib><description>The effects of (−) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects of nicotine on pyramidal cells may thus be a product of complex local circuit interactions.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/0006-8993(91)90520-6</identifier><identifier>PMID: 2054621</identifier><identifier>CODEN: BRREAP</identifier><language>eng</language><publisher>London: Elsevier B.V</publisher><subject>Acetylcholine ; Animals ; Biological and medical sciences ; CA1 ; Dendrites - drug effects ; Dendrites - physiology ; Hippocampus - cytology ; Hippocampus - drug effects ; Hippocampus - physiology ; In Vitro Techniques ; Interneuron ; Interneurons - drug effects ; Interneurons - physiology ; Medical sciences ; Membrane Potentials - drug effects ; Nicotine ; Nicotine - pharmacology ; Pyramidal Tracts - cytology ; Pyramidal Tracts - drug effects ; Pyramidal Tracts - physiology ; Rat hippocampus ; Rats ; Tobacco, tobacco smoking ; Toxicology</subject><ispartof>Brain research, 1991-02, Vol.540 (1), p.287-290</ispartof><rights>1991 Elsevier Science Publishers B.V. (Biomedical Division)</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c418t-7be4cf5ed2e0a1f91dcf0dc7c3ad97caf1dc3e1cb9ad3cf43bb9ca01b676a9513</citedby><cites>FETCH-LOGICAL-c418t-7be4cf5ed2e0a1f91dcf0dc7c3ad97caf1dc3e1cb9ad3cf43bb9ca01b676a9513</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0006-8993(91)90520-6$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19631754$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2054621$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Reece, Laura J.</creatorcontrib><creatorcontrib>Schwartzkroin, Philip A.</creatorcontrib><title>Nicotine exerts differential effects on different CA1 hippocampal cell types</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>The effects of (−) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects of nicotine on pyramidal cells may thus be a product of complex local circuit interactions.</description><subject>Acetylcholine</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>CA1</subject><subject>Dendrites - drug effects</subject><subject>Dendrites - physiology</subject><subject>Hippocampus - cytology</subject><subject>Hippocampus - drug effects</subject><subject>Hippocampus - physiology</subject><subject>In Vitro Techniques</subject><subject>Interneuron</subject><subject>Interneurons - drug effects</subject><subject>Interneurons - physiology</subject><subject>Medical sciences</subject><subject>Membrane Potentials - drug effects</subject><subject>Nicotine</subject><subject>Nicotine - pharmacology</subject><subject>Pyramidal Tracts - cytology</subject><subject>Pyramidal Tracts - drug effects</subject><subject>Pyramidal Tracts - physiology</subject><subject>Rat hippocampus</subject><subject>Rats</subject><subject>Tobacco, tobacco smoking</subject><subject>Toxicology</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFv1DAQhS1E1W5b_gGVcqGCQ1pPnDj2BalaUUBatZdytpzxWBhlk2BnEf33dbqr9gYn22_ePD19Zuw98CvgIK8557JUWouPGj5p3lS8lG_YClRblbKq-Vu2erGcsNOUfuWnEJofs-OKN7WsYMU2dwHHOQxU0F-Kcypc8J4iDXOwfUH5jlkch1e9WN9A8TNM04h2O2UTUt8X8-NE6Zwdedsnenc4z9iP2y8P62_l5v7r9_XNpsQa1Fy2HdXoG3IVcQteg0PPHbYorNMtWp8FQYCdtk6gr0XXabQcOtlKqxsQZ-xynzvF8feO0my2IS017EDjLhnFZaUqVf_XCI3SoJTIxnpvxDimFMmbKYatjY8GuFlomwWlWVAaDeaZtpF57eKQv-u25F6WDnjz_MNhbhPa3kc7YEiv2VoKaJul5-e9jzK1P4GiSRhoQHIh5g8wbgz_LvIEvumcgw</recordid><startdate>19910201</startdate><enddate>19910201</enddate><creator>Reece, Laura J.</creator><creator>Schwartzkroin, Philip A.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19910201</creationdate><title>Nicotine exerts differential effects on different CA1 hippocampal cell types</title><author>Reece, Laura J. ; Schwartzkroin, Philip A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c418t-7be4cf5ed2e0a1f91dcf0dc7c3ad97caf1dc3e1cb9ad3cf43bb9ca01b676a9513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Acetylcholine</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>CA1</topic><topic>Dendrites - drug effects</topic><topic>Dendrites - physiology</topic><topic>Hippocampus - cytology</topic><topic>Hippocampus - drug effects</topic><topic>Hippocampus - physiology</topic><topic>In Vitro Techniques</topic><topic>Interneuron</topic><topic>Interneurons - drug effects</topic><topic>Interneurons - physiology</topic><topic>Medical sciences</topic><topic>Membrane Potentials - drug effects</topic><topic>Nicotine</topic><topic>Nicotine - pharmacology</topic><topic>Pyramidal Tracts - cytology</topic><topic>Pyramidal Tracts - drug effects</topic><topic>Pyramidal Tracts - physiology</topic><topic>Rat hippocampus</topic><topic>Rats</topic><topic>Tobacco, tobacco smoking</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Reece, Laura J.</creatorcontrib><creatorcontrib>Schwartzkroin, Philip A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Reece, Laura J.</au><au>Schwartzkroin, Philip A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nicotine exerts differential effects on different CA1 hippocampal cell types</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>1991-02-01</date><risdate>1991</risdate><volume>540</volume><issue>1</issue><spage>287</spage><epage>290</epage><pages>287-290</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><coden>BRREAP</coden><abstract>The effects of (−) nicotine hydrogen tartrate (NHT) were examined on several cell types in the CA1 region of rat hippocampus. The results indicate that nicotine may have a preferential net inhibitory effect on basket cells and an excitatory effect on oriens/alveus interneurons. The resultant effects of nicotine on pyramidal cells may thus be a product of complex local circuit interactions.</abstract><cop>London</cop><cop>Amsterdam</cop><cop>New York, NY</cop><pub>Elsevier B.V</pub><pmid>2054621</pmid><doi>10.1016/0006-8993(91)90520-6</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 1991-02, Vol.540 (1), p.287-290 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80628284 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Acetylcholine Animals Biological and medical sciences CA1 Dendrites - drug effects Dendrites - physiology Hippocampus - cytology Hippocampus - drug effects Hippocampus - physiology In Vitro Techniques Interneuron Interneurons - drug effects Interneurons - physiology Medical sciences Membrane Potentials - drug effects Nicotine Nicotine - pharmacology Pyramidal Tracts - cytology Pyramidal Tracts - drug effects Pyramidal Tracts - physiology Rat hippocampus Rats Tobacco, tobacco smoking Toxicology |
| title | Nicotine exerts differential effects on different CA1 hippocampal cell types |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T20%3A23%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Nicotine%20exerts%20differential%20effects%20on%20different%20CA1%20hippocampal%20cell%20types&rft.jtitle=Brain%20research&rft.au=Reece,%20Laura%20J.&rft.date=1991-02-01&rft.volume=540&rft.issue=1&rft.spage=287&rft.epage=290&rft.pages=287-290&rft.issn=0006-8993&rft.eissn=1872-6240&rft.coden=BRREAP&rft_id=info:doi/10.1016/0006-8993(91)90520-6&rft_dat=%3Cproquest_cross%3E80628284%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=15891883&rft_id=info:pmid/2054621&rft_els_id=0006899391905206&rfr_iscdi=true |