Improvement of scleromyxedema associated with isotretinoin therapy

The treatment of scleromyxedema has been largely ineffective. We report improvement of scleromyxedema with myopathy after treatment with isotretinoin, 40 mg twice a day. We review other therapeutic modalities used for this disorder and discuss properties of isotretinoin that may have contributed to...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 1991-05, Vol.24 (5), p.854-857
Hauptverfasser:	Hisler, Barbara M., Boyd Savoy, L., Hashimoto, Ken
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Facial Dermatoses - pathology Hand Dermatoses - pathology Humans Isotretinoin - therapeutic use Male Medical sciences Muscular Diseases - pathology Myxedema - drug therapy Myxedema - pathology Pharmacology. Drug treatments Skin Diseases - drug therapy Skin Diseases - pathology Skin, nail, hair, dermoskeleton
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Zusammenfassung:	The treatment of scleromyxedema has been largely ineffective. We report improvement of scleromyxedema with myopathy after treatment with isotretinoin, 40 mg twice a day. We review other therapeutic modalities used for this disorder and discuss properties of isotretinoin that may have contributed to the favorable response.
ISSN:	0190-9622 1097-6787
DOI:	10.1016/0190-9622(91)70132-L