The SOS system of Escherichia coli in the regulation of bacteriophage λ development

A sequence homologous to the known SOS boxes is found in the P o promoter of phage λ. It is suggested that the sequence found is a binding site for the LexA repressor. The mechanism of the LexA part in regulation of λ development is discussed. It is based on the competitive transcription of the RNA...

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Veröffentlicht in:	FEBS letters 1983-08, Vol.160 (1), p.7-10
Hauptverfasser:	Sprizhitsky, Yu.A., Kopylov, V.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacterial Proteins - genetics Bacteriophage lambda - genetics Base Sequence Biological and medical sciences CII protein CII-OOP, competitive transcription DNA Repair Escherichia coli Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Genes, Bacterial Genes, Viral LexA repressor Microbiology OOP-RNA Operon phage lambda Rec A Recombinases Regulation of λ development Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Serine Endopeptidases SOS box Transcription, Genetic Virology
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Beschreibung
Zusammenfassung:	A sequence homologous to the known SOS boxes is found in the P o promoter of phage λ. It is suggested that the sequence found is a binding site for the LexA repressor. The mechanism of the LexA part in regulation of λ development is discussed. It is based on the competitive transcription of the RNA encoding CII protein and the short OOP-RNA transcribed from the P o promoter.
ISSN:	0014-5793 1873-3468
DOI:	10.1016/0014-5793(83)80925-9