A Double-Blind Placebo-Controlled Trial of the Effects of Short-term Potassium Supplementation on Blood Pressure and Atrial Natriuretic Peptide in Normotensive Women

To determine the early effect of potassium loading on blood pressure regulatory mechanisms, the effect of 4 days’ supplementation with 80 mmol/day KCl on blood pressure and vasodilator hormone release was examined using a double-blind crossover design in normotensive women with a baseline potassium excretion of 51.8 ± 2.7 mmol/day. Systolic blood pressure fell 1.7 ± 0.6 mm Hg, (P