Carotid Baroreceptor Function in Dogs With Chronic Norepinephrine Infusion

Carotid baroreceptor function, the compliance of the carotid sinus wall, and the structure of the carotid artery were examined in dogs with elevated plasma norepinephrine (2,000-4,000 pg/ml) for 28 days. The dogs with high norepinephrine were normotensive (100±4.0 versus 98±4.0 mm Hg;/7>0.05) wit...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 1991-06, Vol.17 (6, Part 1), p.745-754
Hauptverfasser:	Wang, Jie, Ochoa, Manuel, Patel, Mrugesh B, Zucker, Irving H, Loud, Alden V, Zeballos, Guillermo A, Hintze, Thomas H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Pressure - drug effects Blood vessels and receptors Carotid Sinus - drug effects Carotid Sinus - physiology Dogs Female Fundamental and applied biological sciences. Psychology Heart Rate - drug effects Hypertension - physiopathology Infusion Pumps, Implantable Male Norepinephrine - administration & dosage Pressoreceptors - drug effects Pressoreceptors - physiology Vertebrates: cardiovascular system
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Zusammenfassung:	Carotid baroreceptor function, the compliance of the carotid sinus wall, and the structure of the carotid artery were examined in dogs with elevated plasma norepinephrine (2,000-4,000 pg/ml) for 28 days. The dogs with high norepinephrine were normotensive (100±4.0 versus 98±4.0 mm Hg;/7>0.05) with bradycardia (65±4.0 versus 87±16 beats/min; p
ISSN:	0194-911X 1524-4563
DOI:	10.1161/01.HYP.17.6.745