Apolipoprotein A-I as a Marker of Angiographically Assessed Coronary-Artery Disease

Apolipoprotein A-I as a Marker of Angiographically Assessed Coronary-Artery Disease

This study was designed to determine whether the plasma level of apolipoprotein A-I is a better discriminator of angiographically documented coronary-artery disease than the level of high-density–lipoprotein (HDL) cholesterol in male subjects. The level of plasma apolipoprotein A-I in 83 patients wi...

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Veröffentlicht in:The New England journal of medicine 1983-08, Vol.309 (7), p.385-389
Hauptverfasser: Maciejko, James J, Holmes, David R, Kottke, Bruce A, Zinsmeister, Alan R, Dinh, Dac M, Mao, Simon J. T
Format: Artikel
Sprache:eng
Schlagworte:
Analysis of Variance
Apolipoprotein A
Apolipoprotein A-I
Apolipoproteins
Apolipoproteins - blood
Apolipoproteins B
Cardiovascular disease
Cholesterol
Cholesterol - blood
Cholesterol, HDL
Coronary Angiography
Coronary artery
Coronary Disease - blood
Coronary Disease - diagnosis
Coronary Disease - diagnostic imaging
High density lipoprotein
Humans
Lipids
Lipoproteins, HDL - blood
Low density lipoprotein
Male
Middle Aged
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Zusammenfassung:This study was designed to determine whether the plasma level of apolipoprotein A-I is a better discriminator of angiographically documented coronary-artery disease than the level of high-density–lipoprotein (HDL) cholesterol in male subjects. The level of plasma apolipoprotein A-I in 83 patients with coronary-artery disease was 96.7±4.2 mg per deciliter (mean ±S.E.M.), which was significantly lower (P
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM198308183090701