Estimation of N-amino- N,N-dimethylaminoethanol, choline and their acetate esters by gas chromatography mass spectrometry

A method is described for measurement of choline, N-aminodeanol, and their acetyl esters by gas chromatography mass spectrometry. The preparation of N-aminodeanol and its isotopic variants is also described. This method allows a thorough quantitative analysis of the replacement of true with false ne...

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Veröffentlicht in:	Analytical biochemistry 1983-04, Vol.130 (1), p.88-94
Hauptverfasser:	Newton, M.W., Ringdahl, B., Jenden, D.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - analysis Chemical Phenomena Chemistry choline Choline - analogs & derivatives Choline - analysis estimation false neurotransmitter Gas Chromatography-Mass Spectrometry method N-amindeeanol Neurotransmitter Agents - analysis
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Beschreibung
Zusammenfassung:	A method is described for measurement of choline, N-aminodeanol, and their acetyl esters by gas chromatography mass spectrometry. The preparation of N-aminodeanol and its isotopic variants is also described. This method allows a thorough quantitative analysis of the replacement of true with false neurotransmitter in biological preparations.
ISSN:	0003-2697 1096-0309
DOI:	10.1016/0003-2697(83)90653-X