Treatment of Childhood Non-Hodgkin's Lymphoma
To the Editor: Anderson and colleagues have reported that survival of children and adolescents with disseminated non-Hodgkin's lymphoma (March 10 issue) was influenced by both the histologic subtype of the disease and the therapeutic regimen followed. 1 Modified LSA 2 -L 2 (a 10-drug regimen) w...
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Veröffentlicht in: | The New England journal of medicine 1983-08, Vol.309 (5), p.310-311 |
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container_title | The New England journal of medicine |
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creator | Weinstein, H J Cassady, J R Lack, E E |
description | To the Editor:
Anderson and colleagues have reported that survival of children and adolescents with disseminated non-Hodgkin's lymphoma (March 10 issue) was influenced by both the histologic subtype of the disease and the therapeutic regimen followed.
1
Modified LSA
2
-L
2
(a 10-drug regimen) was more effective in lymphoblastic lymphoma, whereas COMP (a 4-drug regimen) was more effective in nonlymphoblastic (undifferentiated Burkitt's, undifferentiated pleomorphic, and histiocytic) lymphoma. The undifferentiated and histiocytic lymphomas are a heterogeneous group cytologically, clinically, and immunologically but were analyzed as one group.
2
Because of this grouping the reader cannot evaluate the efficacy of COMP or LSA . . .
No extract is available for articles shorter than 400 words. |
doi_str_mv | 10.1056/NEJM198308043090513 |
format | Article |
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Anderson and colleagues have reported that survival of children and adolescents with disseminated non-Hodgkin's lymphoma (March 10 issue) was influenced by both the histologic subtype of the disease and the therapeutic regimen followed.
1
Modified LSA
2
-L
2
(a 10-drug regimen) was more effective in lymphoblastic lymphoma, whereas COMP (a 4-drug regimen) was more effective in nonlymphoblastic (undifferentiated Burkitt's, undifferentiated pleomorphic, and histiocytic) lymphoma. The undifferentiated and histiocytic lymphomas are a heterogeneous group cytologically, clinically, and immunologically but were analyzed as one group.
2
Because of this grouping the reader cannot evaluate the efficacy of COMP or LSA . . .
No extract is available for articles shorter than 400 words.</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM198308043090513</identifier><identifier>PMID: 6346097</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Antineoplastic Agents - administration & dosage ; Burkitt Lymphoma - drug therapy ; Child ; Drug Administration Schedule ; Humans ; Lymphoma - drug therapy ; Lymphoma, Large B-Cell, Diffuse - drug therapy</subject><ispartof>The New England journal of medicine, 1983-08, Vol.309 (5), p.310-311</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c336t-67f62aefeb7f89e705fe1bbac196304a8e2eeb65873aca71fbbc3f31fea40eaf3</citedby><cites>FETCH-LOGICAL-c336t-67f62aefeb7f89e705fe1bbac196304a8e2eeb65873aca71fbbc3f31fea40eaf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27926,27927,64389</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6346097$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Weinstein, H J</creatorcontrib><creatorcontrib>Cassady, J R</creatorcontrib><creatorcontrib>Lack, E E</creatorcontrib><title>Treatment of Childhood Non-Hodgkin's Lymphoma</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Anderson and colleagues have reported that survival of children and adolescents with disseminated non-Hodgkin's lymphoma (March 10 issue) was influenced by both the histologic subtype of the disease and the therapeutic regimen followed.
1
Modified LSA
2
-L
2
(a 10-drug regimen) was more effective in lymphoblastic lymphoma, whereas COMP (a 4-drug regimen) was more effective in nonlymphoblastic (undifferentiated Burkitt's, undifferentiated pleomorphic, and histiocytic) lymphoma. The undifferentiated and histiocytic lymphomas are a heterogeneous group cytologically, clinically, and immunologically but were analyzed as one group.
2
Because of this grouping the reader cannot evaluate the efficacy of COMP or LSA . . .
No extract is available for articles shorter than 400 words.</description><subject>Antineoplastic Agents - administration & dosage</subject><subject>Burkitt Lymphoma - drug therapy</subject><subject>Child</subject><subject>Drug Administration Schedule</subject><subject>Humans</subject><subject>Lymphoma - drug therapy</subject><subject>Lymphoma, Large B-Cell, Diffuse - drug therapy</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kDFPwzAQhS0EKqXwCxBSJhiQ4ZxznGREUaGgUpYyR05ypilxXOJ06L8nqBUT4pYb3nvf8DF2KeBOQKTuF9OXV5EmCAlIhBQigUdsLCJELiWoYzYGCBMu4xRP2Zn3axhOyHTERgqlgjQeM77sSPeW2j5wJshWdVOtnKuChWv5zFUfn3V744P5zm5WzupzdmJ04-ni8Cfs_XG6zGZ8_vb0nD3MeYmoeq5io0JNhorYJCnFEBkSRaFLkSoEqRMKiQoVJTHqUsfCFEWJBoUhLYG0wQm73nM3nfvaku9zW_uSmka35LY-TyCSiGE4FHFfLDvnfUcm33S11d0uF5D_SMr_kDSsrg74bWGp-t0crAz57T631uctre2_tG-6jW34</recordid><startdate>19830804</startdate><enddate>19830804</enddate><creator>Weinstein, H J</creator><creator>Cassady, J R</creator><creator>Lack, E E</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19830804</creationdate><title>Treatment of Childhood Non-Hodgkin's Lymphoma</title><author>Weinstein, H J ; Cassady, J R ; Lack, E E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c336t-67f62aefeb7f89e705fe1bbac196304a8e2eeb65873aca71fbbc3f31fea40eaf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Antineoplastic Agents - administration & dosage</topic><topic>Burkitt Lymphoma - drug therapy</topic><topic>Child</topic><topic>Drug Administration Schedule</topic><topic>Humans</topic><topic>Lymphoma - drug therapy</topic><topic>Lymphoma, Large B-Cell, Diffuse - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weinstein, H J</creatorcontrib><creatorcontrib>Cassady, J R</creatorcontrib><creatorcontrib>Lack, E E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weinstein, H J</au><au>Cassady, J R</au><au>Lack, E E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of Childhood Non-Hodgkin's Lymphoma</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1983-08-04</date><risdate>1983</risdate><volume>309</volume><issue>5</issue><spage>310</spage><epage>311</epage><pages>310-311</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
Anderson and colleagues have reported that survival of children and adolescents with disseminated non-Hodgkin's lymphoma (March 10 issue) was influenced by both the histologic subtype of the disease and the therapeutic regimen followed.
1
Modified LSA
2
-L
2
(a 10-drug regimen) was more effective in lymphoblastic lymphoma, whereas COMP (a 4-drug regimen) was more effective in nonlymphoblastic (undifferentiated Burkitt's, undifferentiated pleomorphic, and histiocytic) lymphoma. The undifferentiated and histiocytic lymphomas are a heterogeneous group cytologically, clinically, and immunologically but were analyzed as one group.
2
Because of this grouping the reader cannot evaluate the efficacy of COMP or LSA . . .
No extract is available for articles shorter than 400 words.</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>6346097</pmid><doi>10.1056/NEJM198308043090513</doi><tpages>2</tpages></addata></record> |
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language | eng |
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source | MEDLINE; ProQuest Central UK/Ireland |
subjects | Antineoplastic Agents - administration & dosage Burkitt Lymphoma - drug therapy Child Drug Administration Schedule Humans Lymphoma - drug therapy Lymphoma, Large B-Cell, Diffuse - drug therapy |
title | Treatment of Childhood Non-Hodgkin's Lymphoma |
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