Chemical synthesis of glycosaminoglycans : new approaches to antithrombotic drugs

Sanofi, Elf Aquitaine's pharmaceutical subsidiary, is a world leader in the manufacturing of antithrombotic drugs. The development of Heparin-based antithrombotic drugs is traced and the company's progress in producing synthetic substitutes is discussed.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 1991-04, Vol.350 (6319), p.30-33
Hauptverfasser:	PETITOU, M, LORMEAU, J.-C, CHOAY, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Carbohydrate Conformation Carbohydrate Sequence Cardiovascular disease Computer Graphics Corporate profiles Drugs Factor Xa Inhibitors Fibrinolytic Agents - chemical synthesis Glycosaminoglycans - chemical synthesis Heparin - chemistry Humans Medical sciences Models, Molecular Molecular Sequence Data Oligosaccharides - chemical synthesis Oligosaccharides - pharmacology Pharmaceutical industry Pharmacology. Drug treatments Product development Synthetic products
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Beschreibung
Zusammenfassung:	Sanofi, Elf Aquitaine's pharmaceutical subsidiary, is a world leader in the manufacturing of antithrombotic drugs. The development of Heparin-based antithrombotic drugs is traced and the company's progress in producing synthetic substitutes is discussed.
ISSN:	0028-0836 1476-4687