The Pharmacokinetics of temocillin in patients with normal and impaired renal function

The Pharmacokinetics of temocillin in patients with normal and impaired renal function

The pharmacokinctics of temocillin was studied in 16 subjects with varying degrees of renal functional impairment. The subjects were divided into three groups, depending on their creatinine clearance: Group A > 70 ml/min/ 1.73 m2; Group B 20–70ml/min/l.73 m2 and Group C

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Veröffentlicht in:Journal of antimicrobial chemotherapy 1983-04, Vol.11 (4), p.349-356
Hauptverfasser: Boelaert, J., Daneels, R., Schurgers, M., Lambert, A.M., Landuyt, H.W. Van, Mellows, G., Wolf, J., Swaisland, A. J.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Aged
Female
Half-Life
Humans
Kidney Diseases - metabolism
Kinetics
Male
Metabolic Clearance Rate
Middle Aged
Penicillins - administration & dosage
Penicillins - metabolism
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Zusammenfassung:The pharmacokinctics of temocillin was studied in 16 subjects with varying degrees of renal functional impairment. The subjects were divided into three groups, depending on their creatinine clearance: Group A > 70 ml/min/ 1.73 m2; Group B 20–70ml/min/l.73 m2 and Group C
ISSN:0305-7453
1460-2091
DOI:10.1093/jac/11.4.349