The high performance liquid chromatographic measurement of chloramphenicol and its succinate esters in serum

We describe a reliable HPLC procedure for the simultaneous measurement of chloramphenicol and its succinate esters in 30 μL of serum or plasma. The procedure has been applied to assess both the optimum dosing regimen and clinical pharmacokinetics in premature infants.

Bibliographische Detailangaben

Veröffentlicht in:	Clinical biochemistry 1983-06, Vol.16 (3), p.171-177
Hauptverfasser:	Soldin, S.J., Golas, C., Rajchgot, P., Prober, C.G., MacLeod, S.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chloramphenicol - analogs & derivatives Chloramphenicol - blood Chromatography, High Pressure Liquid Humans Infant, Newborn Infant, Premature Kinetics
Online-Zugang:	Volltext
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