Substance P in the human brainstem. Preliminary results of its immunohistochemical localization

Substance P in the human brainstem. Preliminary results of its immunohistochemical localization

The localization of substance P in the human post-mortem brainstem is studied by the indirect immunofluorescence technique. Positive neuronal cell bodies, nerve fibers and terminals are unevenly present over both sensory and effector areas and nuclei. The pattern of distribution of substance P in th...

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Veröffentlicht in:Brain research 1983-03, Vol.264 (1), p.142-147
Hauptverfasser: Del Fiacco, Marina, Dessi, M. Laura, Atzori, M. Gabriella, Levanti, M. Carmela
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aging
Brain Stem - analysis
Brain Stem - growth & development
Brain Stem - pathology
Fluorescent Antibody Technique
human brainstem
Humans
Infant, Newborn
Infant, Premature
Male
neuropeptide immunocytochemistry
substance P
Substance P - analysis
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Zusammenfassung:The localization of substance P in the human post-mortem brainstem is studied by the indirect immunofluorescence technique. Positive neuronal cell bodies, nerve fibers and terminals are unevenly present over both sensory and effector areas and nuclei. The pattern of distribution of substance P in the human brainstem, similar to that seen in the laboratory animals, supports the hypothesis of a neurotransmitter role of this compound in man.
ISSN:0006-8993
1872-6240
DOI:10.1016/0006-8993(83)91132-0