Autosomal dominant ichthyosis exfoliativa

Autosomal dominant ichthyosis exfoliativa

Summary An unusual ichthyosiform dermatosis with circumscribed areas of blistering hyperkeratoses as well as scaly areas was observed in five consecutive generations of a German family. Light and electron microscopical studies revealed oedema of the keratinocytes in the upper epidermis but no defect...

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Veröffentlicht in:British journal of dermatology (1951) 1991-02, Vol.124 (2), p.191-194
Hauptverfasser: VAKILZADEH, F., KOLDE, G.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
Dermatology
Female
Genes, Dominant
Hereditary diseases of the skin. Congenital diseases of the skin. Haemangioma of the skin, of mucosae and of soft tissue
Humans
Ichthyosis - genetics
Ichthyosis - pathology
Medical sciences
Pedigree
Skin - pathology
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Beschreibung
Zusammenfassung:Summary An unusual ichthyosiform dermatosis with circumscribed areas of blistering hyperkeratoses as well as scaly areas was observed in five consecutive generations of a German family. Light and electron microscopical studies revealed oedema of the keratinocytes in the upper epidermis but no defects of tonofilaments and keratohyalin granules. We suggest that this type of ichthyosis exfoliativa inherited as an autosomal dominant trait represents a new and distinct entity.
ISSN:0007-0963
1365-2133
DOI:10.1111/j.1365-2133.1991.tb00432.x