Lower pregnancy rate with premature luteinization during pituitary suppression with leuprolide acetate

Lower pregnancy rate with premature luteinization during pituitary suppression with leuprolide acetate

The relationship of the circulating level of progesterone (P) on the day of human chorionic gonadotropin (hCG) injection to occurrence of clinical pregnancy was examined in 133 leuprolide acetate human menopausal gonadotropin (hMG) in vitro fertilization cycles in women having at least three embryos...

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Veröffentlicht in:Fertility and sterility 1991-03, Vol.55 (3), p.563-566
Hauptverfasser: Schoolcraft, William, Sinton, Eleanor, Schlenker, Terry, Huynh, David, Hamilton, Fredesminda, Meldrum, David R.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
Birth control
Chorionic Gonadotropin - administration & dosage
Drug Administration Schedule
Estradiol - blood
Female
Fertilization in Vitro
Gonadotropin-Releasing Hormone - analogs & derivatives
Gonadotropin-Releasing Hormone - pharmacology
Gynecology. Andrology. Obstetrics
Hormones - pharmacology
Humans
Leuprolide
Luteal Phase - drug effects
Luteinizing Hormone - blood
Medical sciences
Menotropins - therapeutic use
Ovulation Induction
Pituitary Gland - drug effects
Progesterone - blood
Sterility. Assisted procreation
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Zusammenfassung:The relationship of the circulating level of progesterone (P) on the day of human chorionic gonadotropin (hCG) injection to occurrence of clinical pregnancy was examined in 133 leuprolide acetate human menopausal gonadotropin (hMG) in vitro fertilization cycles in women having at least three embryos transferred. Progesterone concentrations>0.5ng/mL were associated with a significantly lower rate of pregnancy (12/59, 20%) compared with
ISSN:0015-0282
1556-5653
DOI:10.1016/S0015-0282(16)54186-7