Molecular models for recognition and activation at the benzodiazepine receptor: A review

In this minireview an overview description of the different pharmacophores that have been proposed for the benzodiazepine receptor is presented. The methodology as well as the experimental information used in the development of each model will be described. Finally, the new experimental discoveries...

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Veröffentlicht in:	Life Sciences 1991, Vol.48 (7), p.593-602
Hauptverfasser:	Villar, H.O., Davies, M.F., Loew, G.H., Maguire, P.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Anxiety Agents - chemistry Anti-Anxiety Agents - metabolism Benzodiazepines Biological and medical sciences Cell receptors Cell structures and functions Fundamental and applied biological sciences. Psychology Miscellaneous Models, Molecular Molecular and cellular biology Molecular Structure Receptors, GABA-A - metabolism reviews
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Beschreibung
Zusammenfassung:	In this minireview an overview description of the different pharmacophores that have been proposed for the benzodiazepine receptor is presented. The methodology as well as the experimental information used in the development of each model will be described. Finally, the new experimental discoveries that are likely to affect the models presented are briefly indicated.
ISSN:	0024-3205 1879-0631
DOI:	10.1016/0024-3205(91)90533-H