The relation between blood organic acid soluble phosphate fractions, citric acid, protein fractions, and lipid fractions in atherosclerotic heart diseases and in lipemias

Blood organic acid soluble phosphate fractions and serum citric acid determinations were performed on 39 carefully chosen cases of atherosclerosis, in order to determine whether any abnormalities might be detected in the oxidative phosphorylation of glucose or in the Krebs tricarboxylic acid cycle, respectively. No differences were observed between a series of normal individuals and atherosclerotic patients. Likewise, serum protein fractionations determined chemically revealed no differences. Only the serum lipid fractions, the total lipids and total cholesterol in particular, were elevated in 60 per cent of the atherosclerotic patients as compared with the normal subjects.