Diabetic nephropathy with superimposed immune complex glomerulonephritis

We describe six diabetic patients with superimposed immune complex glomerulonephritis. Renal manifestations included sudden change in renal function with hematuria in three patients and massive proteinuria in the other three. Renal histology showed the characteristic changes of diabetic nephropathy...

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Veröffentlicht in:	Southern medical journal (Birmingham, Ala.) Ala.), 1983-04, Vol.76 (4), p.456-461
Hauptverfasser:	Sabnis, S G, Antonovych, T T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Basement Membrane - ultrastructure Biopsy Diabetic Nephropathies - complications Diabetic Nephropathies - pathology Female Fluorescent Antibody Technique Glomerulonephritis - complications Glomerulonephritis - immunology Glomerulonephritis - pathology Hematuria - etiology Humans Immune Complex Diseases - complications Immune Complex Diseases - pathology Kidney Glomerulus - ultrastructure Male Microscopy, Electron Middle Aged Proteinuria - etiology
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Zusammenfassung:	We describe six diabetic patients with superimposed immune complex glomerulonephritis. Renal manifestations included sudden change in renal function with hematuria in three patients and massive proteinuria in the other three. Renal histology showed the characteristic changes of diabetic nephropathy along with those of immune complex glomerulonephritis. Biopsy revealed the explanation for the sudden renal changes, thus emphasizing its importance in management of these patients.
ISSN:	0038-4348
DOI:	10.1097/00007611-198304000-00010