Study of anti tetanus IgG and IgM levels in maternal and cord sera by enzyme linked immunosorbent assay (ELISA)

The study was done to determine IgG and IgM antitetanus antibodies in mothers after antenatal immunization, and extent of transfer to the baby as measured by cord levels of tetanus specific IgG and IgM by ELISA using enzyme penicillinase and to study the effect of nutritional status of mothers on an...

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Veröffentlicht in:	Indian journal of pediatrics 1990-11, Vol.57 (6), p.763-770
Hauptverfasser:	SATISH SUNDAR, NEELAM WAGLE, VARUDKAR, B. L, AVINASH VAIDYA, MERCHANT, S. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Enzyme-Linked Immunosorbent Assay Female Fetal Blood - chemistry General aspects Humans Immunoglobulin G - blood Immunoglobulin M - blood Infant, Newborn Infectious diseases Maternal-Fetal Exchange Medical sciences Nutritional Status Pregnancy Prenatal Care Tetanus - immunology Tetanus - prevention & control Tetanus Toxoid - administration & dosage Vaccination
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Beschreibung
Zusammenfassung:	The study was done to determine IgG and IgM antitetanus antibodies in mothers after antenatal immunization, and extent of transfer to the baby as measured by cord levels of tetanus specific IgG and IgM by ELISA using enzyme penicillinase and to study the effect of nutritional status of mothers on antibody response to tetanus toxoid and corresponding cord levels also to determine the number of doses required for protective antibody levels in cord blood. The results obtained in sera of 100 mothers at the time of delivery and their respective cord sera and results of 43 different control sera are discussed using ELISA technique.
ISSN:	0019-5456 0973-7693
DOI:	10.1007/BF02722271