Implantation of tumor xenografts in nude mice: An improved methodology

Implantation of tumor xenografts in nude mice: An improved methodology

Xenografting of neoplasms is a common technique in cancer research. Implantation of non‐uniform tumor tissue fragments often yields tumor nodules of irregular size and shape, which is disadvantageous. We therefore developed a device to standardize size and shape of such implants. This instrument is...

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Veröffentlicht in:Journal of surgical oncology 1991-01, Vol.46 (1), p.40-42
Hauptverfasser: Hudd, CHARLES A. M., La Regina, Marie C., Tolman, Kym C., Johnson, Frank E.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological and medical sciences
Equipment Design
grafting methodology
Male
Medical sciences
Mice
Mice, Nude
Neoplasm Transplantation - methods
Quality Control
Transplantation, Heterologous
tumor implantation
Tumors
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Zusammenfassung:Xenografting of neoplasms is a common technique in cancer research. Implantation of non‐uniform tumor tissue fragments often yields tumor nodules of irregular size and shape, which is disadvantageous. We therefore developed a device to standardize size and shape of such implants. This instrument is effective, inexpensive to fabricate, and simple to use.
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.2930460110