Oncogene from Human EJ Bladder Carcinoma is Located on the Short Arm of Chromosome 11

The human cellular homolog of the transforming DNA sequence isolated from the bladder carcinoma cell line EJ was localized on the short arm of human chromosome 11 by Southern blot analysis of human-rodent hybrid cell DNA. This locus contains human sequences homologous to the Harvey murine sarcoma vi...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1983-02, Vol.219 (4584), p.498-501
Hauptverfasser:	De Martinville, Bérengère, Giacalone, Joseph, Shih, Chiaho, Weinberg, Robert A., Francke, Uta
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cancer research Carcinoma Cell Line Cell lines Chromosome Mapping Chromosomes Chromosomes, Human, 6-12 and X DNA Restriction Enzymes Genes Human chromosomes Humans Hybrid Cells Hybridity Nucleic Acid Hybridization Oncogenes Somatic cells Tumor cell line Urinary Bladder Neoplasms - genetics
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Beschreibung
Zusammenfassung:	The human cellular homolog of the transforming DNA sequence isolated from the bladder carcinoma cell line EJ was localized on the short arm of human chromosome 11 by Southern blot analysis of human-rodent hybrid cell DNA. This locus contains human sequences homologous to the Harvey murine sarcoma virus vHa-ras oncogene.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.6297001