Epidemic of acquired immunodeficiency in rhesus monkeys

A syndrome closely resembling acquired immunodeficiency syndrome (AIDS) in man has been identified in a group of 64 rhesus monkeys (Macaca mulatta) maintained outdoors at the California Primate Research Center. The syndrome is characterised by generalised lymphadenopathy, severe opportunistic infect...

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Veröffentlicht in:	The Lancet (British edition) 1983-02, Vol.1 (8321), p.388-390
Hauptverfasser:	Henrickson, R V, Maul, D H, Osborn, K G, Sever, J L, Madden, D L, Ellingsworth, L R, Anderson, J H, Lowenstine, L J, Gardner, M B
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired Immunodeficiency Syndrome - mortality Acquired Immunodeficiency Syndrome - pathology Acquired Immunodeficiency Syndrome - veterinary AIDS/HIV Animals Bacterial Infections - immunology Bacterial Infections - mortality Bacterial Infections - veterinary California Disease Models, Animal Disease Outbreaks - veterinary Female Fibrosarcoma - immunology Fibrosarcoma - veterinary Macaca - immunology Macaca mulatta - immunology Male Monkey Diseases - immunology Skin Neoplasms - immunology Skin Neoplasms - veterinary Syndrome Virus Diseases - immunology Virus Diseases - mortality Virus Diseases - veterinary
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Beschreibung
Zusammenfassung:	A syndrome closely resembling acquired immunodeficiency syndrome (AIDS) in man has been identified in a group of 64 rhesus monkeys (Macaca mulatta) maintained outdoors at the California Primate Research Center. The syndrome is characterised by generalised lymphadenopathy, severe opportunistic infections including cytomegalovirus, chronic wasting, and high mortality. In 1 animal a multifocal cutaneous fibrosarcoma developed. This syndrome in monkeys may provide an animal model for human AIDS.
ISSN:	0140-6736