Hemophilic splenic rupture without thrombocytosis

Spontaneous splenic rupture in hemophilia A is an uncommon occurrence which is difficult to diagnose. We have reported a case of hemophilic rupture of the spleen unaccompanied by thrombocytosis, which has been emphasized as a diagnostic clue to hemophilic splenic rupture. Hence, splenic rupture should still be considered in any hemophilic patient with pain in the left upper quadrant and a normal platelet count. Splenic rupture in hemophilia must be recognized because its treatment requires not only clotting factor infusion but also surgical intervention.