Therapy of malignant APUD cell tumors: Effectiveness of DTIC

Eleven patients with malignant APUD tumors, five islet cell carcinomas, five carcinoid tumors and one medullary carcinoma of the thyroid were treated with DTIC. Nine of 11 patients benefitted from treatment. A literature review revealed that other APUD tumors responded when treated with DTIC. DTIC i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer 1983-03, Vol.51 (5), p.790-794
Hauptverfasser: Kessinger, Anne, Foley, John F., Lemon, Henry M.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 794
container_issue 5
container_start_page 790
container_title Cancer
container_volume 51
creator Kessinger, Anne
Foley, John F.
Lemon, Henry M.
description Eleven patients with malignant APUD tumors, five islet cell carcinomas, five carcinoid tumors and one medullary carcinoma of the thyroid were treated with DTIC. Nine of 11 patients benefitted from treatment. A literature review revealed that other APUD tumors responded when treated with DTIC. DTIC is a useful agent for treatment of malignant APUDomas, and may be the drug of choice for islet cell carcinoma of the pancreas.
doi_str_mv 10.1002/1097-0142(19830301)51:5<790::AID-CNCR2820510507>3.0.CO;2-3
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_80356150</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>80356150</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4667-d56710378cde09fb02261bc600f8685812464ae3b9b9ea91535760cc5b25e8f73</originalsourceid><addsrcrecordid>eNqVkN1Kw0AQhRdRaq0-gpAr0YvU2d3sT2oRalq1UKxIC-LNkKQbjSRNzbZK396EVkEvBGFhWM6ZMzMfIVcU2hSAnVPwlQvUY6fU1xw40DNBO6KrfOh0esO-G9wFD0wzEBQEqEvehnYwvmAu3yHN7-Zd0gQA7QqPP-6TA2tfq69igjdIQzJfSOo1SXfyYspwsXaKxMnDLH2eh_Ol07uf9p3YZJmzXOVFaTvOIElMvEzfzdxYW5v7k2FwSPaSMLPmaFtbZHo9mAS37mh8Mwx6Izf2pFTuTEhFgSsdzwz4SQSMSRrFEiDRUgtNmSe90PDIj3wT-lRwoSTEsYiYMDpRvEVONrmLsnhbGbvEPLX1euHcFCuLGnh1jYDK-LQxxmVhbWkSXJRpHpZrpIA1WqzpYE0Hv9CiqB5WaBErtPgTLXIEDMbIkFfhx9stVlFuZt_RW5aVbjb6R5qZ9b8m_zn4l8I_Ad0bkuc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80356150</pqid></control><display><type>article</type><title>Therapy of malignant APUD cell tumors: Effectiveness of DTIC</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Kessinger, Anne ; Foley, John F. ; Lemon, Henry M.</creator><creatorcontrib>Kessinger, Anne ; Foley, John F. ; Lemon, Henry M.</creatorcontrib><description>Eleven patients with malignant APUD tumors, five islet cell carcinomas, five carcinoid tumors and one medullary carcinoma of the thyroid were treated with DTIC. Nine of 11 patients benefitted from treatment. A literature review revealed that other APUD tumors responded when treated with DTIC. DTIC is a useful agent for treatment of malignant APUDomas, and may be the drug of choice for islet cell carcinoma of the pancreas.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(19830301)51:5&lt;790::AID-CNCR2820510507&gt;3.0.CO;2-3</identifier><identifier>PMID: 6295614</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adenoma, Islet Cell - drug therapy ; Adult ; Aged ; Apudoma - drug therapy ; Carcinoid Tumor - drug therapy ; Carcinoma - drug therapy ; Dacarbazine - therapeutic use ; Female ; Humans ; Ileal Neoplasms - drug therapy ; Male ; Middle Aged ; Neoplasm Metastasis ; Pancreatic Neoplasms - drug therapy ; Thyroid Neoplasms - drug therapy</subject><ispartof>Cancer, 1983-03, Vol.51 (5), p.790-794</ispartof><rights>Copyright © 1983 American Cancer Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c4667-d56710378cde09fb02261bc600f8685812464ae3b9b9ea91535760cc5b25e8f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6295614$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kessinger, Anne</creatorcontrib><creatorcontrib>Foley, John F.</creatorcontrib><creatorcontrib>Lemon, Henry M.</creatorcontrib><title>Therapy of malignant APUD cell tumors: Effectiveness of DTIC</title><title>Cancer</title><addtitle>Cancer</addtitle><description>Eleven patients with malignant APUD tumors, five islet cell carcinomas, five carcinoid tumors and one medullary carcinoma of the thyroid were treated with DTIC. Nine of 11 patients benefitted from treatment. A literature review revealed that other APUD tumors responded when treated with DTIC. DTIC is a useful agent for treatment of malignant APUDomas, and may be the drug of choice for islet cell carcinoma of the pancreas.</description><subject>Adenoma, Islet Cell - drug therapy</subject><subject>Adult</subject><subject>Aged</subject><subject>Apudoma - drug therapy</subject><subject>Carcinoid Tumor - drug therapy</subject><subject>Carcinoma - drug therapy</subject><subject>Dacarbazine - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Ileal Neoplasms - drug therapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neoplasm Metastasis</subject><subject>Pancreatic Neoplasms - drug therapy</subject><subject>Thyroid Neoplasms - drug therapy</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkN1Kw0AQhRdRaq0-gpAr0YvU2d3sT2oRalq1UKxIC-LNkKQbjSRNzbZK396EVkEvBGFhWM6ZMzMfIVcU2hSAnVPwlQvUY6fU1xw40DNBO6KrfOh0esO-G9wFD0wzEBQEqEvehnYwvmAu3yHN7-Zd0gQA7QqPP-6TA2tfq69igjdIQzJfSOo1SXfyYspwsXaKxMnDLH2eh_Ol07uf9p3YZJmzXOVFaTvOIElMvEzfzdxYW5v7k2FwSPaSMLPmaFtbZHo9mAS37mh8Mwx6Izf2pFTuTEhFgSsdzwz4SQSMSRrFEiDRUgtNmSe90PDIj3wT-lRwoSTEsYiYMDpRvEVONrmLsnhbGbvEPLX1euHcFCuLGnh1jYDK-LQxxmVhbWkSXJRpHpZrpIA1WqzpYE0Hv9CiqB5WaBErtPgTLXIEDMbIkFfhx9stVlFuZt_RW5aVbjb6R5qZ9b8m_zn4l8I_Ad0bkuc</recordid><startdate>19830301</startdate><enddate>19830301</enddate><creator>Kessinger, Anne</creator><creator>Foley, John F.</creator><creator>Lemon, Henry M.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19830301</creationdate><title>Therapy of malignant APUD cell tumors: Effectiveness of DTIC</title><author>Kessinger, Anne ; Foley, John F. ; Lemon, Henry M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4667-d56710378cde09fb02261bc600f8685812464ae3b9b9ea91535760cc5b25e8f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Adenoma, Islet Cell - drug therapy</topic><topic>Adult</topic><topic>Aged</topic><topic>Apudoma - drug therapy</topic><topic>Carcinoid Tumor - drug therapy</topic><topic>Carcinoma - drug therapy</topic><topic>Dacarbazine - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Ileal Neoplasms - drug therapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neoplasm Metastasis</topic><topic>Pancreatic Neoplasms - drug therapy</topic><topic>Thyroid Neoplasms - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kessinger, Anne</creatorcontrib><creatorcontrib>Foley, John F.</creatorcontrib><creatorcontrib>Lemon, Henry M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kessinger, Anne</au><au>Foley, John F.</au><au>Lemon, Henry M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Therapy of malignant APUD cell tumors: Effectiveness of DTIC</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1983-03-01</date><risdate>1983</risdate><volume>51</volume><issue>5</issue><spage>790</spage><epage>794</epage><pages>790-794</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><abstract>Eleven patients with malignant APUD tumors, five islet cell carcinomas, five carcinoid tumors and one medullary carcinoma of the thyroid were treated with DTIC. Nine of 11 patients benefitted from treatment. A literature review revealed that other APUD tumors responded when treated with DTIC. DTIC is a useful agent for treatment of malignant APUDomas, and may be the drug of choice for islet cell carcinoma of the pancreas.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>6295614</pmid><doi>10.1002/1097-0142(19830301)51:5&lt;790::AID-CNCR2820510507&gt;3.0.CO;2-3</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0008-543X
ispartof Cancer, 1983-03, Vol.51 (5), p.790-794
issn 0008-543X
1097-0142
language eng
recordid cdi_proquest_miscellaneous_80356150
source MEDLINE; Alma/SFX Local Collection
subjects Adenoma, Islet Cell - drug therapy
Adult
Aged
Apudoma - drug therapy
Carcinoid Tumor - drug therapy
Carcinoma - drug therapy
Dacarbazine - therapeutic use
Female
Humans
Ileal Neoplasms - drug therapy
Male
Middle Aged
Neoplasm Metastasis
Pancreatic Neoplasms - drug therapy
Thyroid Neoplasms - drug therapy
title Therapy of malignant APUD cell tumors: Effectiveness of DTIC
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T02%3A24%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Therapy%20of%20malignant%20APUD%20cell%20tumors:%20Effectiveness%20of%20DTIC&rft.jtitle=Cancer&rft.au=Kessinger,%20Anne&rft.date=1983-03-01&rft.volume=51&rft.issue=5&rft.spage=790&rft.epage=794&rft.pages=790-794&rft.issn=0008-543X&rft.eissn=1097-0142&rft_id=info:doi/10.1002/1097-0142(19830301)51:5%3C790::AID-CNCR2820510507%3E3.0.CO;2-3&rft_dat=%3Cproquest_cross%3E80356150%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=80356150&rft_id=info:pmid/6295614&rfr_iscdi=true