Epithelial damage beyond the tip of the endotracheal tube

The effects of ventilator rate and inspired humidity on the large airway epithelium of newborn lambs have been studied using scanning electron microscopy. Significant deciliation, denudation and necrosis occurred at both high and conventional rates if the inspired gas had low humidity. The damage ob...

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Veröffentlicht in:	Early human development 1990-12, Vol.24 (3), p.187-200
Hauptverfasser:	Todd, David A., John, Elizabeth, Osborn, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Bronchi - pathology deciliation Epithelium - pathology Female Humidity inspired humidity Intubation, Intratracheal - adverse effects Male Microscopy, Electron, Scanning newborn Pulmonary Ventilation Respiration, Artificial scanning electron microscopy Sheep Trachea - pathology ventilation rate
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Zusammenfassung:	The effects of ventilator rate and inspired humidity on the large airway epithelium of newborn lambs have been studied using scanning electron microscopy. Significant deciliation, denudation and necrosis occurred at both high and conventional rates if the inspired gas had low humidity. The damage observed was mild in the high humidity groups.
ISSN:	0378-3782 1872-6232
DOI:	10.1016/0378-3782(90)90026-F