SARUBICIN B, A NEW QUINONE ANTIBIOTIC, ISOLATED FROM THE FERMENTATION BROTH OF A STREPTOMYCES STRAIN

SARUBICIN B, A NEW QUINONE ANTIBIOTIC, ISOLATED FROM THE FERMENTATION BROTH OF A STREPTOMYCES STRAIN

Sarubicin B, isolated from the culture filtrate of a Streptomyces strain JA 2861, is a new quinone antibiotic. The compound was isolated as an orange crystalline powder, mp 282-284°C. In vitro sarubicin B was found to inhibit Gram-positive bacteria. It was not active against Gram-negative microorgan...

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Veröffentlicht in:Journal of antibiotics 1982, Vol.35(12), pp.1638-1640
Hauptverfasser: ECKARDT, KLAUS, TRESSELT, DIETER, IHN, WOLFGANG, BRADLER, GERTRAUD, REINHARDT, G.
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - biosynthesis
Anti-Bacterial Agents - pharmacology
Bacteria - drug effects
Chemical Phenomena
Chemistry, Physical
Fermentation
Mass Spectrometry
Naphthoquinones - biosynthesis
Naphthoquinones - pharmacology
Streptomyces - metabolism
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Beschreibung
Zusammenfassung:Sarubicin B, isolated from the culture filtrate of a Streptomyces strain JA 2861, is a new quinone antibiotic. The compound was isolated as an orange crystalline powder, mp 282-284°C. In vitro sarubicin B was found to inhibit Gram-positive bacteria. It was not active against Gram-negative microorganisms.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.35.1638