Use of the 82Sr/ 82Rb Generator in Clinical PET Studies
The use of the 82Sr/ 82Rb generator in clinical positron emission tomography (PET) studies of myocardial perfusion has been described. An infusion pump is used to deliver the short-lived 82Rb from the generator to the patient. Various characteristics of the generator and the infusion system are desc...
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Veröffentlicht in: | International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology Nuclear medicine and biology, 1990, Vol.17 (8), p.763,767-765,768 |
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container_title | International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology |
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creator | Saha, Gopal B. Go, Raymundo T. Macintyre, William J. Marwick, Thomas H. Beachler, Annette King, Janet L. Neumann, Donald R. |
description | The use of the
82Sr/
82Rb generator in clinical positron emission tomography (PET) studies of myocardial perfusion has been described. An infusion pump is used to deliver the short-lived
82Rb from the generator to the patient. Various characteristics of the generator and the infusion system are described. The
82Rb yield was 69.8 ± 13.3% and the
82Sr breakthrough was always less than the limit of 0.02 μCi/mCi
82Rb. The yield of
82Rb increased with the flow rate and the potency of the generator. Patients with coronary artery disease were studied for myocardial perfusion abnormalities by the
82Rb PET technique and images of excellent diagnostic quality were obtained. |
doi_str_mv | 10.1016/0883-2897(90)90023-T |
format | Article |
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82Sr/
82Rb generator in clinical positron emission tomography (PET) studies of myocardial perfusion has been described. An infusion pump is used to deliver the short-lived
82Rb from the generator to the patient. Various characteristics of the generator and the infusion system are described. The
82Rb yield was 69.8 ± 13.3% and the
82Sr breakthrough was always less than the limit of 0.02 μCi/mCi
82Rb. The yield of
82Rb increased with the flow rate and the potency of the generator. Patients with coronary artery disease were studied for myocardial perfusion abnormalities by the
82Rb PET technique and images of excellent diagnostic quality were obtained.</description><identifier>ISSN: 0883-2897</identifier><identifier>DOI: 10.1016/0883-2897(90)90023-T</identifier><identifier>PMID: 2079423</identifier><identifier>CODEN: NMBIEO</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Biological and medical sciences ; Coronary Circulation ; Coronary Disease - diagnostic imaging ; Coronary Disease - physiopathology ; Humans ; Infusion Pumps ; Investigative techniques, diagnostic techniques (general aspects) ; Medical sciences ; Miscellaneous. Technology ; Radionuclide Generators ; Radionuclide investigations ; Rubidium Radioisotopes - administration & dosage ; Tomography, Emission-Computed</subject><ispartof>International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1990, Vol.17 (8), p.763,767-765,768</ispartof><rights>1990</rights><rights>1993 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2333-5fa8508360b2833dfe948714bc3ae4a7d0727593f405250f766c9f1ad3e685f73</citedby><cites>FETCH-LOGICAL-c2333-5fa8508360b2833dfe948714bc3ae4a7d0727593f405250f766c9f1ad3e685f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,4012,27912,27913,27914</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4484989$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2079423$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saha, Gopal B.</creatorcontrib><creatorcontrib>Go, Raymundo T.</creatorcontrib><creatorcontrib>Macintyre, William J.</creatorcontrib><creatorcontrib>Marwick, Thomas H.</creatorcontrib><creatorcontrib>Beachler, Annette</creatorcontrib><creatorcontrib>King, Janet L.</creatorcontrib><creatorcontrib>Neumann, Donald R.</creatorcontrib><title>Use of the 82Sr/ 82Rb Generator in Clinical PET Studies</title><title>International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology</title><addtitle>Int J Rad Appl Instrum B</addtitle><description>The use of the
82Sr/
82Rb generator in clinical positron emission tomography (PET) studies of myocardial perfusion has been described. An infusion pump is used to deliver the short-lived
82Rb from the generator to the patient. Various characteristics of the generator and the infusion system are described. The
82Rb yield was 69.8 ± 13.3% and the
82Sr breakthrough was always less than the limit of 0.02 μCi/mCi
82Rb. The yield of
82Rb increased with the flow rate and the potency of the generator. Patients with coronary artery disease were studied for myocardial perfusion abnormalities by the
82Rb PET technique and images of excellent diagnostic quality were obtained.</description><subject>Biological and medical sciences</subject><subject>Coronary Circulation</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Coronary Disease - physiopathology</subject><subject>Humans</subject><subject>Infusion Pumps</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Medical sciences</subject><subject>Miscellaneous. Technology</subject><subject>Radionuclide Generators</subject><subject>Radionuclide investigations</subject><subject>Rubidium Radioisotopes - administration & dosage</subject><subject>Tomography, Emission-Computed</subject><issn>0883-2897</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kFFLwzAQx_OgzDn9Bgp9ENGHujRJm-RFkDGnMFBc9xzS9IKRrtWkFfz2Zm7s0Zc7uP_vjuOH0EWG7zKcFVMsBE2JkPxG4luJMaFpeYTGh_EJOg3hI84Fy_kIjQjmkhE6RnwdIOls0r9DIsjKT2N9q5IFtOB13_nEtcmsca0zukle52Wy6ofaQThDx1Y3Ac73fYLWj_Ny9pQuXxbPs4dlagilNM2tFjkWtMAVEZTWFiQTPGOVoRqY5jXmhOeSWoZzkmPLi8JIm-maQiFyy-kEXe_ufvrua4DQq40LBppGt9ANQQlMZCEZjSDbgcZ3IXiw6tO7jfY_KsNq60htZaitDCWx-nOkyrh2ub8_VBuoD0t7QTG_2uc6RAXW69a4cMAYE0wKGbH7HQbRxbcDr4Jx0BqonQfTq7pz___xC320gJg</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Saha, Gopal B.</creator><creator>Go, Raymundo T.</creator><creator>Macintyre, William J.</creator><creator>Marwick, Thomas H.</creator><creator>Beachler, Annette</creator><creator>King, Janet L.</creator><creator>Neumann, Donald R.</creator><general>Elsevier Ltd</general><general>Pergamon</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1990</creationdate><title>Use of the 82Sr/ 82Rb Generator in Clinical PET Studies</title><author>Saha, Gopal B. ; Go, Raymundo T. ; Macintyre, William J. ; Marwick, Thomas H. ; Beachler, Annette ; King, Janet L. ; Neumann, Donald R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2333-5fa8508360b2833dfe948714bc3ae4a7d0727593f405250f766c9f1ad3e685f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Biological and medical sciences</topic><topic>Coronary Circulation</topic><topic>Coronary Disease - diagnostic imaging</topic><topic>Coronary Disease - physiopathology</topic><topic>Humans</topic><topic>Infusion Pumps</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Medical sciences</topic><topic>Miscellaneous. Technology</topic><topic>Radionuclide Generators</topic><topic>Radionuclide investigations</topic><topic>Rubidium Radioisotopes - administration & dosage</topic><topic>Tomography, Emission-Computed</topic><toplevel>online_resources</toplevel><creatorcontrib>Saha, Gopal B.</creatorcontrib><creatorcontrib>Go, Raymundo T.</creatorcontrib><creatorcontrib>Macintyre, William J.</creatorcontrib><creatorcontrib>Marwick, Thomas H.</creatorcontrib><creatorcontrib>Beachler, Annette</creatorcontrib><creatorcontrib>King, Janet L.</creatorcontrib><creatorcontrib>Neumann, Donald R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saha, Gopal B.</au><au>Go, Raymundo T.</au><au>Macintyre, William J.</au><au>Marwick, Thomas H.</au><au>Beachler, Annette</au><au>King, Janet L.</au><au>Neumann, Donald R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of the 82Sr/ 82Rb Generator in Clinical PET Studies</atitle><jtitle>International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology</jtitle><addtitle>Int J Rad Appl Instrum B</addtitle><date>1990</date><risdate>1990</risdate><volume>17</volume><issue>8</issue><spage>763,767</spage><epage>765,768</epage><pages>763,767-765,768</pages><issn>0883-2897</issn><coden>NMBIEO</coden><abstract>The use of the
82Sr/
82Rb generator in clinical positron emission tomography (PET) studies of myocardial perfusion has been described. An infusion pump is used to deliver the short-lived
82Rb from the generator to the patient. Various characteristics of the generator and the infusion system are described. The
82Rb yield was 69.8 ± 13.3% and the
82Sr breakthrough was always less than the limit of 0.02 μCi/mCi
82Rb. The yield of
82Rb increased with the flow rate and the potency of the generator. Patients with coronary artery disease were studied for myocardial perfusion abnormalities by the
82Rb PET technique and images of excellent diagnostic quality were obtained.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>2079423</pmid><doi>10.1016/0883-2897(90)90023-T</doi><tpages>6</tpages></addata></record> |
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subjects | Biological and medical sciences Coronary Circulation Coronary Disease - diagnostic imaging Coronary Disease - physiopathology Humans Infusion Pumps Investigative techniques, diagnostic techniques (general aspects) Medical sciences Miscellaneous. Technology Radionuclide Generators Radionuclide investigations Rubidium Radioisotopes - administration & dosage Tomography, Emission-Computed |
title | Use of the 82Sr/ 82Rb Generator in Clinical PET Studies |
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