Study of the Mode of Action of Ribosomal Vaccines from Klebsiella and Streptococcus pneumoniae and Their Ribonucleic and Protein Fractions Using Passive Immunization

The vaccinating potency of ribosomal fractions of Klebsiella pneumoniae and Streptococcus pneumoniae as well as their ribosomal RNA and protein fractions has been studied with respect to their ability to induce cellular or humoral immunity. Experiments with transfer of serum or spleen cells from vac...

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Veröffentlicht in:	Microbiology and immunology 1982-01, Vol.26 (10), p.933-940
Hauptverfasser:	Robert, Daniel, Ivanoff, Bernard, Fontanges, Robert, Normier, Gérard, Pinel, Anne Marie, D'Hinterland, Lucien Dussourd
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Proteins - immunology Bacterial Vaccines - immunology Female Immunization, Passive Klebsiella pneumoniae Klebsiella pneumoniae - immunology Male Mice Mice, Inbred BALB C Ribosomes - immunology RNA, Bacterial - immunology RNA, Ribosomal - immunology Spleen - immunology Streptococcus Streptococcus pneumoniae Streptococcus pneumoniae - immunology
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Beschreibung
Zusammenfassung:	The vaccinating potency of ribosomal fractions of Klebsiella pneumoniae and Streptococcus pneumoniae as well as their ribosomal RNA and protein fractions has been studied with respect to their ability to induce cellular or humoral immunity. Experiments with transfer of serum or spleen cells from vaccinated animals have shown that anti‐Klebsiella immunity is essentially cellular, while streptococcal immunity is exclusively humoral. Results have been discussed as a function of differential results for the various fractions under study.
ISSN:	0385-5600 1348-0421
DOI:	10.1111/j.1348-0421.1982.tb00239.x