An automated assay for the determination of asparaginase activity
Accurate and precise determinations of activity are required during the production of the drug asparaginase. Experience in a control laboratory situation has shown that manual enzymatic activity assays have a high degree of variability between chemists because of slight differences in technique. An...
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| Veröffentlicht in: | Journal of biological standardization 1982-01, Vol.10 (4), p.297-301 |
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| container_end_page | 301 |
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| container_issue | 4 |
| container_start_page | 297 |
| container_title | Journal of biological standardization |
| container_volume | 10 |
| creator | Toncic, Pauline F. Tibbetts, Donald L. |
| description | Accurate and precise determinations of activity are required during the production of the drug asparaginase. Experience in a control laboratory situation has shown that manual enzymatic activity assays have a high degree of variability between chemists because of slight differences in technique. An automated assay for the determination of asparaginase activity was developed. It reproduces exactly the same assay conditions each time it is run. The procedure is fast, precise, accurate, and has eliminated technician to technician variability. |
| doi_str_mv | 10.1016/S0092-1157(82)80005-X |
| format | Article |
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Experience in a control laboratory situation has shown that manual enzymatic activity assays have a high degree of variability between chemists because of slight differences in technique. An automated assay for the determination of asparaginase activity was developed. It reproduces exactly the same assay conditions each time it is run. 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Experience in a control laboratory situation has shown that manual enzymatic activity assays have a high degree of variability between chemists because of slight differences in technique. An automated assay for the determination of asparaginase activity was developed. It reproduces exactly the same assay conditions each time it is run. 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Experience in a control laboratory situation has shown that manual enzymatic activity assays have a high degree of variability between chemists because of slight differences in technique. An automated assay for the determination of asparaginase activity was developed. It reproduces exactly the same assay conditions each time it is run. The procedure is fast, precise, accurate, and has eliminated technician to technician variability.</abstract><cop>England</cop><pub>Elsevier Science (USA)</pub><pmid>7153219</pmid><doi>10.1016/S0092-1157(82)80005-X</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0092-1157 |
| ispartof | Journal of biological standardization, 1982-01, Vol.10 (4), p.297-301 |
| issn | 0092-1157 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80254553 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Asparaginase - analysis Asparaginase - standards Autoanalysis - methods |
| title | An automated assay for the determination of asparaginase activity |
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