Synthesis of 4-Carboxymethylthio-Substituted Steroids for Enzyme Immunoassay

The 4-carboxymethylthio derivatives 8 and 13, new haptens of betamethasone (2) and dexamethasone (1), were prepared for application to enzyme immunoassay.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical & pharmaceutical bulletin 1990/08/25, Vol.38(8), pp.2268-2270
Hauptverfasser:	NISHIGUCHI, Yoshino, TAGAWA, Noriko, WATANABE, Fukuko, KIGUCHI, Toshiko, NINOMIYA, Ichiya
Format:	Artikel
Sprache:	eng
Schlagworte:	4-(carboxymethylthio)betamethasone 4-(carboxymethylthio)dexamethasone Alicyclic compounds, terpenoids, prostaglandins, steroids betamethasone Betamethasone - analogs & derivatives Betamethasone - chemical synthesis carboxymethylthiolation Chemistry dexamethasone Dexamethasone - analogs & derivatives Dexamethasone - chemical synthesis enzyme immunoassay Exact sciences and technology hapten Immunoenzyme Techniques Indicators and Reagents - chemical synthesis Organic chemistry Preparations and properties Steroids
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Beschreibung
Zusammenfassung:	The 4-carboxymethylthio derivatives 8 and 13, new haptens of betamethasone (2) and dexamethasone (1), were prepared for application to enzyme immunoassay.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.38.2268