Enzyme immunoassay of oestrogen and progesterone receptors in uterine and intrauterine tissue during human pregnancy and labour

Oestrogen and progesterone receptors were studied in the non-pregnant state, in early pregnancy and at term using monoclonal antibody enzyme immunoassays. Receptors for both steroids were found in tissues from non-pregnant patients and patients in early pregnancy. At term oestrogen receptors were un...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 1990-11, Vol.37 (4), p.509-511
Hauptverfasser:	Padayachi, T., Pegoraro, R.J., Rom, L., Joubert, S.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amnion - metabolism Antibodies, Monoclonal Biological and medical sciences Chorion - metabolism Decidua - metabolism Female Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation Humans Immunoenzyme Techniques Labor, Obstetric - metabolism Myometrium - metabolism Placenta - metabolism Pregnancy - metabolism Pregnancy. Parturition. Lactation Receptors, Estrogen - analysis Receptors, Estrogen - metabolism Receptors, Progesterone - analysis Receptors, Progesterone - metabolism Uterus - metabolism Vertebrates: reproduction
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Beschreibung
Zusammenfassung:	Oestrogen and progesterone receptors were studied in the non-pregnant state, in early pregnancy and at term using monoclonal antibody enzyme immunoassays. Receptors for both steroids were found in tissues from non-pregnant patients and patients in early pregnancy. At term oestrogen receptors were undetectable in all tissues studied. Progesterone receptors were undetectable in chorion, amnion and placenta at term, while present in extremely low concentrations in decidua and myometrium.
ISSN:	0960-0760 1879-1220
DOI:	10.1016/0960-0760(90)90394-Z