PREPARATION AND CHARACTERIZATION OF DEDESOSAMINYL 5-O-MYCAMINOSYL-10, 11-DIHYDROMYCINAMICIN IV
During the course of search for new antibiotics produced by Micromonospora sp., in addition to the formation of AR-5 (mycinamicin) antibiotics, the authors isolated three neutral components which were characterized from their spectroscopic (PMR, CMR and MS) data. These compounds were named as mycino...
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| Veröffentlicht in: | Journal of antibiotics 1982, Vol.35(10), pp.1407-1408 |
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| container_issue | 10 |
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| container_title | Journal of antibiotics |
| container_volume | 35 |
| creator | LOTVIN, JASON PUAR, MOHINDAR S. PATEL, MAHESH LEE, BONG K. SCHUMACHER, D. WALTZ, J. ALLAN |
| description | During the course of search for new antibiotics produced by Micromonospora sp., in addition to the formation of AR-5 (mycinamicin) antibiotics, the authors isolated three neutral components which were characterized from their spectroscopic (PMR, CMR and MS) data. These compounds were named as mycinolide IV, dedesosaminylmycinamicin IV and dedesosaminylmycinamicin V. It was envisioned that a non-antibiotic producing blocked-mutant may be utilized to produce an antibiotic by glycosidation at C-5 of the neutral isolates. The authors now disclose the formation of dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV. |
| doi_str_mv | 10.7164/antibiotics.35.1407 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0021-8820 |
| ispartof | The Journal of Antibiotics, 1982, Vol.35(10), pp.1407-1408 |
| issn | 0021-8820 1881-1469 |
| language | eng |
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| source | J-STAGE Free; MEDLINE |
| subjects | Anti-Bacterial Agents - biosynthesis Anti-Bacterial Agents - isolation & purification Chemical Phenomena Chemistry Fermentation Leucomycins - biosynthesis Leucomycins - isolation & purification Macrolides Magnetic Resonance Spectroscopy Micromonospora |
| title | PREPARATION AND CHARACTERIZATION OF DEDESOSAMINYL 5-O-MYCAMINOSYL-10, 11-DIHYDROMYCINAMICIN IV |
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