Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids
Laminin is a multichain extracellular matrix glycoprotein found primarily in basement membranes. The molecule is made up of three subunits, designated as A, B1, and B2. Using an 850-base cDNA probe for the mouse laminin A-chain and a 1000-base cDNA probe for the mouse laminin B2 chain, we have scree...
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| Veröffentlicht in: | Somatic cell and molecular genetics 1990-11, Vol.16 (6), p.599-603 |
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| container_title | Somatic cell and molecular genetics |
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| creator | WEBER KAYE, N CHUNG, A. E LALLEY, P. A DURKIN, M. E PHILLIPS, S. L CHURCH, R. L |
| description | Laminin is a multichain extracellular matrix glycoprotein found primarily in basement membranes. The molecule is made up of three subunits, designated as A, B1, and B2. Using an 850-base cDNA probe for the mouse laminin A-chain and a 1000-base cDNA probe for the mouse laminin B2 chain, we have screened mouse-Chinese hamster somatic cell hybrids in order to assign the genes for each of these polypeptides to their respective mouse chromosome. We have determined that the mouse laminin B2-chain gene is located on chromosome 1 (confirming this assignment) and the laminin A-chain gene is located on chromosome 17. |
| doi_str_mv | 10.1007/BF01233101 |
| format | Article |
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We have determined that the mouse laminin B2-chain gene is located on chromosome 1 (confirming this assignment) and the laminin A-chain gene is located on chromosome 17.</description><identifier>ISSN: 0740-7750</identifier><identifier>EISSN: 1572-9931</identifier><identifier>DOI: 10.1007/BF01233101</identifier><identifier>PMID: 2267633</identifier><identifier>CODEN: SCMGDN</identifier><language>eng</language><publisher>London: Plenum</publisher><subject>Animals ; Biological and medical sciences ; Blotting, Southern ; Classical genetics, quantitative genetics, hybrids ; Fundamental and applied biological sciences. Psychology ; Genetics of eukaryotes. 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We have determined that the mouse laminin B2-chain gene is located on chromosome 1 (confirming this assignment) and the laminin A-chain gene is located on chromosome 17.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Blotting, Southern</subject><subject>Classical genetics, quantitative genetics, hybrids</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetics of eukaryotes. Biological and molecular evolution</subject><subject>Hybrid Cells</subject><subject>Laminin - genetics</subject><subject>Mice</subject><subject>Vertebrata</subject><issn>0740-7750</issn><issn>1572-9931</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0DFPwzAQBWALgUopLOxIXmBACpztxHbGtqIFqRILzMFxbGoUOyVOhv57UojodMN9enp6CF0TeCAA4nGxAkIZI0BO0JRkgiZ5zsgpmoJIIREig3N0EeMXAEjJsgmaUMoFZ2yKPtYmGOzVbufCJ24s9k0fDa6Vd8EFPMcqVHhBcezLPrgu4j4e4K9KllsXzKC3ysfOtDg2XnVOY23qGm_3ZeuqeInOrKqjuRrvDL2vnt6Wz8nmdf2ynG8STanoEpILqdKyZFYoaWxe6koYEGBpSpmxNAdeZhwqmVHNpS6VykVWUeBVBtIwymbo7i931zbfvYld4V08FFHBDGULCRSoYHyA939Qt02MrbHFrnVetfuCQHGYszjOOeCbMbUvvan-6bjf8L8d_ypqVdtWBe3iMTFPh8Jcsh8A-nu8</recordid><startdate>199011</startdate><enddate>199011</enddate><creator>WEBER KAYE, N</creator><creator>CHUNG, A. E</creator><creator>LALLEY, P. A</creator><creator>DURKIN, M. E</creator><creator>PHILLIPS, S. 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We have determined that the mouse laminin B2-chain gene is located on chromosome 1 (confirming this assignment) and the laminin A-chain gene is located on chromosome 17.</abstract><cop>London</cop><cop>New York, NY</cop><pub>Plenum</pub><pmid>2267633</pmid><doi>10.1007/BF01233101</doi><tpages>5</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Animals Biological and medical sciences Blotting, Southern Classical genetics, quantitative genetics, hybrids Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Hybrid Cells Laminin - genetics Mice Vertebrata |
| title | Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids |
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